Microbial fermentation processes - Optimize fermentors
Industrial fermentations, microbial kinetics, oxygen and CO2 in fermentors, optimal operations of batch, continuous and fed-batch fermentations
ONLINE COURSE: On-demand
COURSE FEE: 350 € per session
COURSE ORGANIZATION
Course organized in 6 sessions
Sessions can be taken individually
Scheduling: suggested one session per week
Effort: 3 - 6 hours per session
COURSE DESCRIPTION
The course provides a comprehensive overview of industrial fermentation processes, including their technologies, operations, scale-up, and cost optimization. It reviews the kinetics of microbial transformations, the solubilities and transfer kinetics of oxygen and CO2. It provides in-depth insights into the optimal operations of batch, continuous, and fed-batch fermentations..
The course features a combination of methodological presentations and fermentation case studies.
INSTRUCTOR
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Jean-Marc Engasser, BioProcess Digital
DIGITAL LEARNING
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Learning platform with course resources
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Live or recorded slideshow presentations
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Case studies on spreadsheet templates with guides and corrections
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Online collective or one-to-one tutoring
COURSE PROGRAM
SESSION 1: INDUSTRIAL FERMENTATION PROCESSES
Microorganisms, media, products. Process operations. Fermentors technologies and operations. Fermentation costs
SESSION 2: MICROBIAL KINETICS
KInetic analysis in batch and continuous fermentors. Microbial kinetic laws. Industrial fermentations kinetics
SESSION 3: OXYGEN AND CO2 IN FERMENTORS
Fermentors aeration technologies. Solubilities and transfer kinetics. Determination of oxygen transfer coefficient
SESSION 4: BATCH FERMENTATIONS OPTIMAL OPERATIONS
Batch fermentations principles, kinetics and productivities. Optimization of anaerobic and aerobic fermentations
SESSION 5: CONTINUOUS FERMENTATIONS OPTIMAL OPERATIONS
Continuous fermentations principles. Dynamic and steady-state kinetics. Optimization of anaerobic and aerobic fermentations
SESSION 6: FED-BATCH FERMENTATIONS OPTIMAL OPERATIONS
Fed-batch fermentations principles, operation and kinetics. Optimization of fermentations for biomass and metabolites